Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia
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چکیده
منابع مشابه
Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.
Schizophrenia is a neurodevelopmental disorder that affects up to 1% of the general population. Various genes show associations with schizophrenia and a very weak nominal association with the tight junction protein, claudin-5, has previously been identified. Claudin-5 is expressed in endothelial cells forming part of the blood-brain barrier (BBB). Furthermore, schizophrenia occurs in 30% of ind...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2017
ISSN: 1359-4184,1476-5578
DOI: 10.1038/mp.2017.156